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هموفیلی - تاریخچة هموفیلی
یکشنبه 26 اردیبهشت 1389  09:12 ب.ظ

قدیمی‌ترین آثار هموفیلی در مصر و فراعنه مومیائی شده دیده شده است.
قبل از قرن نوزدهم آثار مدون دربارة هموفیلی در تورات است كه جودا خاخام كلیمی پسر یك بانوی حامل هموفیلی را از ختنه معاف كرد. بنابر این كلیمی‌های قدیم احتمال خونریزی را در هموفیل می‌شناختند.
در قرن دوازدهم میلادی خلف بن عباس نویسنده ال تصریف وجود هموفیلی را در یك قریه عرب گزارش داد كه مردان از خونریزی فوت می‌كردند.

در قرن نوزدهم در 1803 یك پزشك آمریكائی در فیلادلفیا شجره هموفیلی را رسم كرد و قانون ناسه (NASSE) كه فرزندان هموفیلی سالم و بعضی از نوه‌ها دچار بیماری می‌شوند را گزارش داد.
اولین بیمار درمان شده هموفیلی در 1840 میلادی بود كه با تزریق خون درمان شد.
در پادشاهان قدیم اروپا هموفیلی وجود داشته است. ملكه ویكتوریا دارای ژن هموفیلی بود. احتمالاً پدر وی جهش را در اسپرم خود داشت و ملكه حامل ژن شد و در اعقاب وی هموفیلی وجود داشته است. الكساندرا همسر نیكولای حامل هموفیلی بود. وی نتیجه ملكه ویكتوریا پادشاه انگلستان بود، خونریزی‌های مكرر فرزند الكساندرا بنام الكسی موجب نفوذ راسپوتین كشیش به دربار تزار شد. كه با دعای مكرر فرزند تزار را درمان می‌كرد.
بروز هموفیلی در خانواده پادشاهی اسپانیا از طریق دختر ملكه ویكتوریا كه همسر الفونسو پادشاه اسپانیا شد به ثبت رسیده است.


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